Elucidation of the Mechanism Underlying the Anti-Inflammatory Properties of (S)-(+)-Carvone Identifies a Novel Class of Sirtuin-1 Activators in a Murine Macrophage Cell Line.

On the contrary, Bay 11-7082 (5 μM), a selective NF-κB inhibitor, decreased LPS-induced IκB-α phosphorylation and degradation ( Figure 3 a,b), although the difference relative to cells treated with LPS alone did not reach statistical significance.

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