A variable-gain stochastic pooling motif mediates information transfer from receptor assemblies into NF-κB.

Although properties of IL-1– and TNF-induced puncta did not show a clear trend across doses, IL-1–induced spots were significantly larger and brighter than their TNF-induced CI counterparts ( Fig. 2C and movie S2; for all comparisons, P << 10 −10 , Student’s t test).

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