However, not only is EF-G (and EF2) mediated GTP hydrolysis [ 180 ] very important for speed, though its initial binding may contribute to some relevant loss of contacts, in part by stabilizing tRNA:mRNA pairing in the A-site, it is overall hugely significant for restraining unselected frameshifting and enabling selected 3′ frameshift stimulators to function [ 108 , 181 , 182 , 183 ].
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From Recoding to Peptides for MHC Class I Immune Display: Enriching Viral Expression, Virus Vulnerability and Virus Evasion.
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