Myeloid-Derived Suppressor Cells Dampen Airway Inflammation Through Prostaglandin E2 Receptor 4.

Front Immunol · 2021 · PMC8311661 · PMID 34322123

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Both PMN- and M-MDSCs isolated from the lungs of asthmatic mice treated with the EP4 agonist L-902,688 showed a trend of increased immunosuppressive activity with increasing doses of agonist compared to MDSCs isolated from PBS-treated asthmatic mice ( Figures 5D, E ).

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