<i>In vitro</i> OP9-DL1 co-culture and subsequent maturation in the presence of IL-21 generates tumor antigen-specific T cells with a favorable less-differentiated phenotype and enhanced functionality.

Oncoimmunology · 2021 · PMC8312599 · PMID 34367734

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showed a trendno p-value reported

Also, combining IL-15 and IL-21 showed a trend toward a higher fold expansion during agonist selection as compared to IL-15 or IL-21 alone ( Figure 3(a )).

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