Like in spo11-3HA pch2Δ , the pattern of spore death in the spo11-3HA GFP-NLS-PCH2 homozygous strain showed a trend to the excess of tetrads with four-, two- and zero-viable spores, indicative of meiosis I nondisjunction events ( Fig 5B , bottom graph; [ 58 ]).
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Pch2 orchestrates the meiotic recombination checkpoint from the cytoplasm.
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