Tackling cardiometabolic risk in the Asia Pacific region.

An extensive cohort study from Japan reports an interesting trend.

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In their report, East, Southeast Asia, and South Asia showed a trend towards higher mean systolic blood pressure, while high-income Asia Pacific countries including Singapore, South Korea, and Japan showed a declining mean systolic blood pressure.

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While blinded cross-over studies have demonstrated a fairly significant nocebo effect [ 33 ], the reality in clinical practice is that these symptoms have the potential to promote either inappropriate dose reduction or elimination of statin therapy altogether in these patients.

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