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Association between sacubitril/valsartan initiation and real-world health status trajectories over 18 months in heart failure with reduced ejection fraction.

ESC Heart Fail · 2021 · PMC8318450 · PMID 33932120

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Although physical limitations improved to a greater extent among the ARNI cohort as compared with the non‐ARNI cohort, this did not reach statistical significance at 12 months.

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