Systemic infection exacerbates cerebrovascular dysfunction in Alzheimer's disease.

Brain · 2021 · PMC8320299 · PMID 33723589

Europe PMC DOI

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did not reach statistical significanceno p-value reported

MAG:PLP1 tended to be lower, and VEGF and PDGFRβ tended to be higher, in individuals heterozygous or homozygous for APOE ε4 but these differences did not reach statistical significance.

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highly significantno p-value reported

Two-way ANOVA revealed a highly significant interaction effect between infection and dementia status for MAG:PLP1 in both Alzheimer’s disease and vascular dementia patients ( Supplementary Table 2 ).

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