EOMES and IL-10 regulate antitumor activity of T regulatory type 1 CD4⁺ T cells in chronic lymphocytic leukemia.

CD4 + T-cell counts in spleen showed a trend toward a higher number of Il10rb −/− CD4 + T cells compared to WT T cells per spleen (Supplementary Fig. 7A ), which is likely a reflection of the bigger spleen sizes in the Il10rb −/ − group, as the number of CD4 + T cells per CLL cell was reduced in these mice in comparison to the WT group (Fig. 6B ).

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