Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency.

There was a trend toward more plasmablasts in Cgas −/− BM and Cgas −/− + dKO BM mice than in dKO controls ( Figure 4 F), but this effect did not reach statistical significance despite the large number of mice analyzed (n = 14–16).

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