Thyroid function, renal events and mortality in chronic kidney disease patients: the German Chronic Kidney Disease study.

Cross-sectional association of TFMs and thyroid functional status with eGFR Table 2 shows the cross-sectional associations of various thyroid traits on eGFR (mL/min/1.73 m 2 ). For TFMs added singularly to the regression model, FT3 (pmol/L) showed a highly significant positive association with eGFR (per 1 pmol/L increase of FT3, eGFR was 2.99 mL/min/1.73 m 2 higher; P = 1.6e–15).

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In the GCKD study we were able to detect higher UACR values for hypothyroid patients compared with euthyroid patients, but the association of low-FT3 syndrome with hypothyroidism was only nominally significant, most likely due to small case numbers for hypothyroidism.

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