A matrix of structure-based designs yields improved VRC01-class antibodies for HIV-1 therapy and prevention.

MAbs · 2021 · PMC8331036 · PMID 34328065

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a clear trendno p-value reported

In addition, we observed a clear trend in rank-order for potency of the light-chain variants, with 3aa_del the most potent followed by 2aa_del_V3S and by wild-type.

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