Myeloid-resident neuropilin-1 influences brown adipose tissue in obesity.

Surprisingly, after 12 weeks of diet, LysM-Cre:Nrp1 fl/fl mice on HFD showed significantly higher total or normalized weights of both iBAT and iWAT when compared to LysM-Cre:Nrp1 wt/wt mice, whereas eWAT showed a trend, but was not significant, despite eWAT weight being significantly higher after 4 weeks of diet in LysM-Cre:Nrp1 fl/fl mice (Fig. 2 D–F, Supplemental Figure 1D–M).

also in 53,322 other papers