Prognostic Value and Potential Immunoregulatory Role of SCARF1 in Hepatocellular Carcinoma.

Front Oncol · 2020 · PMC8336907 · PMID 34354939

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highly significantno p-value reported

Consequently, all of the endothelial markers selected ( ADGRF5, CD93, FLT4, MMRN2, ESAM, PEAR1, PECAM1, TIE1 , and CLEC14A ) exhibited a highly significant positive correlation with SCARF1 expression ( Figure S3 ).

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a strong trendno p-value reported

scavenger receptor leukocyte recruitment tumor endothelial cells liver cancer tumor microenviroment Mauritius Research Council 10.13039/501100011856 MR/R010013/1 Rosetrees Trust 10.13039/501100000833 Utilizing qPCR analysis, we have previously shown a strong trend for decreased SCARF1 mRNA expression in HCC tumor tissue compared to normal liver tissue ( 14 ); here, we corroborated this finding with publically-available RNA-sequencing data from The Cancer Genome Atlas (TGCA).

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