Barely Significant
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Echocardiography for latent rheumatic heart disease in first degree relatives of children with acute rheumatic fever: Implications for active case finding in family members.

EClinicalMedicine · 2021 · PMC8343257 · PMID 34386737

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Whilst Definite RHD prevalence in biologic parents of children with ARF was nearly twice the background population rate (4% compared to 2.3%), this did not reach statistical significance.

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