Mechanical plus oral bowel preparation with paromomycin and metronidazole reduces infectious complications in elective colorectal surgery: a matched case-control study.

Finally, the oral antibiotic administration led to an almost significantly reduced length of stay (12.24 days vs 15.25 days; p = 0.057).

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With regard to the surgical approach, preoperative bowel decontamination showed a significant decrease in SSI in open surgery ( p = 0.018), but a less remarkable effect in laparoscopic surgery ( p = 0.263). Intraabdominal abscesses (OR 0.714, 95% CI 0.235–2.169) or anastomotic leakage (OR 0.571; 95% CI 0.167–1.952) showed a trend towards a decreased frequency in the IG, but did not reach a significant level.

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