Seven-month kinetics of SARS-CoV-2 antibodies and role of pre-existing antibodies to human coronaviruses.

At the first cross-sectional visit (M0, mean days PSO = 20) levels of all three Ig isotypes against RBD and S antigens positively correlated with neutralization capacity ( r s = 0.19–0.32, p < 0.05), while the correlation between antibody levels against N and RBD-ACE2 neutralization did not reach statistical significance (Fig. 3A ).

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