Synthesis and Biological Assessment of 4,1-Benzothiazepines with Neuroprotective Activity on the Ca²⁺ Overload for the Treatment of Neurodegenerative Diseases and Stroke.

As it can be appreciated in Figure 5 , dimethylamino analogues 21 , 26 , 27 , and 28 present a clear trend to protect against oxidative stress, as these compounds are able to reduce the cell death induced by R/O.

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