Evidence of a Muscle-Brain Axis by Quantification of the Neurotrophic Myokine METRNL (Meteorin-Like Protein) in Human Cerebrospinal Fluid and Serum.

J Clin Med · 2021 · PMC8347672 · PMID 34362056

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highly significantno p-value reported

The basal permeability was proven by the highly significant correlation between serum and CSF METRNL concentrations and by specific calculation of the relatively high CSF/serum ratio of 1.4 ± 0.8.

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a significant trendno p-value reported

This indicates that individuals with higher serum METRNL levels overall have a significant trend to higher CSF concentrations.

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