Barely Significant
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Activation of Peripheral Blood Mononuclear Cells and Leptin Secretion: New Potential Role of Interleukin-2 and High Mobility Group Box (HMGB)1.

Int J Mol Sci · 2021 · PMC8347813 · PMID 34360753

Europe PMCDOI
2
hedged sentences
0.0587
closest p · 1.2× alpha
0.0587
boldest claim

The sentences

almost significantp = 0.0587so close (0.05 < p ≤ 0.1)
Total PBMCs had an almost significant increase in leptin secretion after incubation with 25 mM glucose vs. 5.5 mM glucose ( p = 0.0587) and a significant increase after treatment with 45 mM glucose compared to 5.5 mM glucose ( p < 0.0005) and 25 mM glucose ( p < 0.005) ( Figure 6 A).

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nearly statistically significantno p-value reported
Moreover, IL-2 and HMGB1 significantly increased TNF-α secretion compared with HMGB1 alone or control ( p < 0.05) ( Figure 1 D), and nearly statistically significant vs.

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