KEAP1/NFE2L2 Mutations of Liquid Biopsy as Prognostic Biomarkers in Patients With Advanced Non-Small Cell Lung Cancer: Results From Two Multicenter, Randomized Clinical Trials.

Front Oncol · 2021 · PMC8350725 · PMID 34381706

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a negative trendno p-value reported

reported a negative trend in the association between the GSEA enrichment score of DDR-related pathways and TMB ( 24 ), which also validates a higher TMB in KEAP1/NFE2L2 with mutations than in wild-type due to the lack of DDR gene expression.

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