Myocardial fibrosis reversion via rhACE2-electrospun fibrous patch for ventricular remodeling prevention.

NPJ Regen Med · 2021 · PMC8355140 · PMID 34376690

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Both IM and rhACE2 patch group showed a trend of better systolic function preservation compared to PLLA group, reflected by left ventricular ejection fraction (PLLA: 27 ± 11%, IM: 31 ± 3%, PLLA-HA/ACE2: 31 ± 14%) and fractional shortening (PLLA: 10 ± 8%, IM: 15 ± 2%, PLLA-HA/ACE2: 15 ± 7%) (Fig. 6c, d ).

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