Longitudinal ex vivo and molecular trends of chloroquine and piperaquine activity against Plasmodium falciparum and P. vivax before and after introduction of artemisinin-based combination therapy in Papua, Indonesia.

Int J Parasitol Drugs Drug Resist · 2021 · PMC8358472 · PMID 34193398

Europe PMC DOI

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a significant trendno p-value reported

In contrast, there was a significant trend for increasing PIP IC 50 s in both Plasmodium species from 2010 onwards.

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