showed a trendP = .053
However, SLC6A4 TC/CC carriers showed a trend for softer stools (according to the BSS) compared with TT carriers ( P = .053). 3.8 Impact of DNA variants on transcription factor binding capacity We performed comparative transcription factor binding site analysis in the major and the minor (protective) haplotype genomic regions where the tag SNP rs2020938 resides.