TDP-43 and FUS mislocalization in VCP mutant motor neurons is reversed by pharmacological inhibition of the VCP D2 ATPase domain.

Brain Commun · 2021 · PMC8361416 · PMID 34396115

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did not reach statistical significanceno p-value reported

However, although ML240 treatment resulted in an increase in the nuclear-to-cytoplasmic ratio (Average; UT = 0.90, ML240 = 0.97), this difference did not reach statistical significance for SFPQ ( Fig. 3G–I ).

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