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Influenza vaccination in cancer patients receiving immune checkpoint inhibitors: A systematic review.

Eur J Clin Invest · 2021 · PMC8365730 · PMID 34021591

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6 One study comparing the safety of ICIs in 385 vaccinated and 149 nonvaccinated patients showed a trend towards lower incidence of irAEs in vaccinated patients 25 ; finally, one small study reported a trend towards lower incidence of irAEs in nonvaccinated patients. 26 The results of the eight studies assessing the efficacy of influenza vaccination in 986 patients with cancer receiving ICIs are summarized in Table 2 . 6 , 19 , 21 , 22 , 23 , 25 , 27 , 28 , 29 No pooled descriptive analysis was conducted due to the heterogeneity of efficacy endpoints and reporting of data.

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