did not reach statistical significancep value = 0.3
Of the 26 patients with baseline misuse and follow-up data, the fraction of patients whose pMDI technique improved to correct use (≥ 9 correct steps) was lower in those with mild cognitive impairment (63% improved) and dementia (63% improved) than those with normal cognition (90% improved), although this trend did not reach statistical significance ( p value = 0.3 by Fisher’s exact test) (Fig. 1 ).