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Efficacy of a Novel Bi-Steric mTORC1 Inhibitor in Models of B-Cell Acute Lymphoblastic Leukemia.

Front Oncol · 2021 · PMC8366290 · PMID 34408976

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The combination of dasatinib with RMC-4627 inhibited mTORC1 substrate phosphorylation to an apparently greater extent than treatment with individual agents, but this did not reach statistical significance.

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