Barely Significant
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Effect of Collagen Hydrolysate and Fish Oil on High-Sensitivity C-Reactive Protein and Glucose Homeostasis in Patients with severe Burn; a Randomized Clinical Trial.

Arch Acad Emerg Med · 2021 · PMC8366458 · PMID 34405148

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Conclusion Supplementation with collagen hydrolysate and omega-3 FAs improved hs-CRP concentration and insulin resistance in patients with major burns, although the latter did not reach statistical significance.

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a decreasing trendno p-value reported
In the collagen+omega-3 group, 88.9% of patients had a decreasing trend in HOMA-IR from baseline to the end of the study, while 73.7% of patients in the collagen and 58.8% in the control group had such a trend, and the rest of patients in each group had increased insulin resistance throughout the study. 3.4.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.