TPPU treatment of burned mice dampens inflammation and generation of bioactive DHET which impairs neutrophil function.

Blockage of p38MAPK showed a trend to increase ROS production in CD62L + ICAM-1- and CD62L + ICAM-1 + neutrophils, however not statistically significantly (0 vs SB) (Fig. 3 F,J), but did decrease ROS production in the CD62L-ICAM-1- and CD62L-ICAM-1 + (0 vs SB) populations significantly (Fig. 3 H,L).

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