In another study, in which the overall rate of colitis was 2.3% across all ICI, the RR of colitis with anti-CTLA-4 use vs anti-PD-1/anti-PD-L1 use was higher, although it did not reach statistical significance ( P = 0.054)[ 30 ].
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Immune checkpoint inhibitor-mediated colitis in gastrointestinal malignancies and inflammatory bowel disease.
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0.0540
0.0540