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Higher VO<sub>2</sub>max is associated with thicker cortex and lower grey matter blood flow in older adults.

Sci Rep · 2021 · PMC8373929 · PMID 34408221

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showed a trendno p-value reported
Cardiovascular fitness, measured as VO 2 max, was inversely associated with hippocampal blood flow and showed a trend for an inverse association with mean GMBF, in contrast with our hypotheses of a positive relation between VO 2 max and GMBF.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.