Although the membrane potentials (MP) of RGCs showed a trend toward depolarization in TNF-α injected retinas, there was no significant difference between control and TNF-α injected groups (Fig. 1 a, c).
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Soluble tumor necrosis factor-alpha-induced hyperexcitability contributes to retinal ganglion cell apoptosis by enhancing Nav1.6 in experimental glaucoma.
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