Polymyxins, the last-resort antibiotics: Mode of action, resistance emergence, and potential solutions.

J Biosci · 2021 · PMC8387214 · PMID 34475315

Europe PMC

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quite significantno p-value reported

This finding of the plasmid-borne gene mcr-1 is quite significant considering that it could be acquired horizontally leading to the rapid development of polymyxin resistance (Ayoub Moubareck 2020 ; Mmatli et al. 2020 ; Poirel et al. 2017b ).

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