Anti-MRSA Cephalosporin versus Vancomycin-Based Treatment for Acute Bacterial Skin and Skin Structure Infection: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Antibiotics (Basel) · 2021 · PMC8388936 · PMID 34439070

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did not reach statistical significanceno p-value reported

Further analysis showed that the clinical response rate was numerically lower in ceftaroline or ceftobiprole compared to vancomycin-based treatment, but the difference did not reach statistical significance (ceftaroline: OR, 0.73; 95% CI, 0.41–1.29; I 2 = 0%; ceftobiprole: OR, 0.49; 95% CI, 0.24–1.02; I 2 = 0%).

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