MicroRNAs as Potential Predictors of Response to CDK4/6 Inhibitor Treatment.

Combination treatment with MIR9 and CDK4/6 inhibitor ribociclib synergized in luminal and HER2-positive breast cancer cell lines, although the interaction failed to reach statistical significance [ 43 ]. miR-200b: Endothelial expression of miR-200b was suppressed by more than 50% during lung tumor development. miR-200b was shown to negatively regulate the expression of quaking (QKI), an RNA-binding protein that implicates in endothelial maturation and proliferation.

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