Is the Morphological Subtype of Extra-Pulmonary Neuroendocrine Carcinoma Clinically Relevant?

Cancers (Basel) · 2021 · PMC8392018 · PMID 34439308

Europe PMC DOI

hedged sentence

0.0670

closest p · 1.3× alpha

0.0670

boldest claim

The sentences

showed a trendp = 0.067so close (0.05 < p ≤ 0.1)

The non-SC subtype was an independent prognostic factor for both worse PFS (adjusted-HR = 1.62; p = 0.016) and OS (adjusted-HR = 1.64; p = 0.015), whereas a Ki-67 index of ≥55% (significantly enriched in the SC subgroup; Table 1 ) was an independent prognostic factor for worse PFS (adjusted-HR = 1.80; p = 0.028) and showed a trend towards worse OS (adjusted-HR = 1.63; p = 0.067).

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