Gut Microbiota Dynamics during Chemotherapy in Epithelial Ovarian Cancer Patients Are Related to Therapeutic Outcome.

Six months after the end of the treatments, the proportions of Dialister in PS patients who received adjuvant chemotherapy tended to remain higher ( p = 0.1), while in PS patients of the neoadjuvant group, there were significant or near-significant increases in some PR-associated microbial signatures, i.e., Eggerthella ( p = 0.1) and Adlercreutzia ( p = 0.04) ( Figure S7 ).

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As discussed above for the whole cohort, an overall trend towards reduced alpha diversity in the first treatment cycles was observed across all study groups ( Figure 3 A).

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