Poloxamer 188 Exerts Direct Protective Effects on Mouse Brain Microvascular Endothelial Cells in an In Vitro Traumatic Brain Injury Model.

Even though 1 mM P188 showed a trend to increase tNOp in HR+C exposed MBEC, this difference was not statistically significant ( Figure 7 D).

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Even though a climbing trend of tNOp was visible in HR+C exposed cells, this trend failed to achieve significance.

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M, regardless of treatment (CN-C, CN+C, HR-C, HR+C), increased significantly by adding 10 μM, 100 μM and 1 mM P188, except for 1 mM P188 in HR+C where an increase seemed to occur, but failed to reach significance.

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