However, these two therapeutic options showed a clear trend towards a protective effect against GDM and HDP.
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Exercise versus Metformin to Improve Pregnancy Outcomes among Overweight Pregnant Women: A Systematic Review and Network Meta-Analysis.
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Hypertensive Disorders of Pregnancy Table 2 B, Figure 2 B, and Figure S1B show that no intervention produced a significant effect on pairwise comparisons or NMA, although metformin almost reached statistical significance in the NMA (RR = 0.47, 95% CI = 0.22, 1.04). 3.3.