The tumour mutational burden (TMB) was significantly lower in single nodal metastasis compared to the paired primary breast cancer ( P = 0.0021), while the decline in TMB did not reach statistical significance in the MLNs group ( P = 0.083).
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Genetic and immune characteristics of sentinel lymph node metastases and multiple lymph node metastases compared to their matched primary breast tumours.
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0.0830
0.0830