Adjuvant Effect of Orally Applied Preparations Containing Non-Digestible Polysaccharides on Influenza Vaccination in Healthy Seniors: A Double-Blind, Randomised, Controlled Pilot Trial.

Instead, positive trends and close-to-significant findings of this study should be regarded indicative of effects that should be verified in a confirmatory, large-scale randomised trial, for which it was calculated that over 110 subjects per intervention arm would be required to detect stimulatory effects of AX on vaccine-mediated increases in HI seroprotection rate against influenza A H1N1.

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