Although there was as an apparent increase in TLR4 expression in animals receiving the TLR4 antagonist (from 251.7 ± 33.4 in the OA-vehicle group to 324.7 ± 41.0 in OA-TLR4A1 animals), it did not reach statistical significance.
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TLR4 Antagonism Reduces Movement-Induced Nociception and ATF-3 Expression in Experimental Osteoarthritis.
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