2,3,7,8-Tetrachlorodibenzo-p-Dioxin (TCDD)-Inducible Poly-ADP-Ribose Polymerase (TIPARP/PARP7) Catalytic Mutant Mice (TiparpH532A) Exhibit Increased Sensitivity to TCDD-Induced Hepatotoxicity and Lethality.

Toxicol Sci · 2021 · PMC8404992 · PMID 34129049

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did not reach statistical significanceno p-value reported

Although there was a trend for increased Cyp1a1 mRNA levels in treated Tiparp H532A compared with Tiparp +/+ mice, this difference did not reach statistical significance ( Figure 5A ).

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