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A humanized orthotopic tumor microenvironment alters the bone metastatic tropism of prostate cancer cells.

Commun Biol · 2021 · PMC8405640 · PMID 34462519

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showed a trendno p-value reported
The humanized prostate TME showed a trend to decrease metastasis of PC-3 PCa cells to the tissue-engineered bone, but did not affect the metastatic potential of PCa cells to the endogenous murine bones or organs.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.