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Association of Plasma Pro-Brain-Derived Neurotrophic Factor (proBDNF)/Mature Brain-Derived Neurotrophic Factor (mBDNF) Levels with BDNF Gene Val66Met Polymorphism in Alcohol Dependence.

Med Sci Monit · 2021 · PMC8406813 · PMID 34415897

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In the current study, we found that in the alcohol-dependent patients only, the level of proBDNF in the plasma with Met/Met (AA) genotype was slightly higher than that with Val/Val (GG) and Val/Met (AG) genotypes, while the level of mBDNF was slightly lower; however, it did not reach statistical significance.

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