Barely Significant
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Augmented ustekinumab dosing is needed to achieve clinical response in patients with anti-TNF refractory pediatric Crohn's disease: a retrospective chart review.

F1000Res · 2020 · PMC8408544 · PMID 34504690

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a clear trendno p-value reported
They provide visual aid and show a clear trend of improvement for patients on augmented dosing.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.