showed a trendp = 0.178
High dose group showed a trend to have higher incidence of grade 3–4 CRS than low dose group without reaching a statistical significance (8.4%, 95%CI −0.009–0.177; I 2 = 34.5%, p = 0.178 vs 1.6%, 95%CI −0.026–0.058; I 2 = 0.0%, p = .939) ( z = 1.53, P = .127) ( Figure 9(C) ). 3.4.