Gene expression atlas of energy balance brain regions.

Results of GSEA are as follows: monogenic obesity genes were significantly enriched in the arcuate nucleus of the hypothalamus and showed a trend of enrichment in the embryonic hypothalamus ( Supplemental Figure 6, A and B ); rare coding variants were significantly enriched in embryonic hypothalamus and hindbrain ( Supplemental Figure 6, A and C ); low-frequency coding variants were enriched in hypothalamic regions, significantly in the dors

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We observed a nonsignificant trend of enrichment of T1D-associated genes in the cerebellum in the GSEA analysis ( Figure 6 and Supplemental Figure 11A ).

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